NEWS
This study discusses and emphasizes the decoupling and precise control of the mechanical and structural features of bioscaffolds in skin regeneration outcomes.
We developed fibrotic microniches that recapitulate the interaction of liver sinusoid endothelial cells and hepatic stellate cells, and revealed a new mechanism for fibrosis progression.
We present the protocol to fabricate versatile 3D microtissues and their applications in regenerative therapy and drug screening.
We designed a pathology-targeted cell delivery strategy leveraging injectable micro-scaffolds as cell-loading capsule and endogenous tissue transglutaminase at lesion site as adhesive.
We established a high-throughput drug screening platform based on biomechanically primed hepatic stromal stellate cells to recapitulate state-specific liver microtumors.
This study develops thermoresponsive hydrogels with controllable stiffness to generate mechanically primed cells with intact mechanical memory for augmented wound healing.
恭喜王婧宇入选首届博士后创新人才支持计划!
This study demonstrates that cellular heterogeneity regulated by substrate stiffness is evident starting from the initial single-cell stage until the resulting multi-cellular stage through distinguished proliferative patterns.
We tested the 3D culture of hepatocytes and revealed that 3D enhanced hepatic functions through regulating the EMT status.
Congratulations to all scholarship winners in our lab.